NIH Patents and Patent Applications

This list includes non-provisional and PCT patent filings.

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Lead IC Reference Number Title Country Patent Application Type Application Number Date Filed Patent Number Date Issued Patent Status Patent PDF
NIAID E-160-2021-0-EP-01 AUGMENTATION OF INNATE AND ADAPTIVE IMMUNITY BY INHIBITION OF INTERACTION OF LILRBS WITH MHC-1 EP National Stage 22803142.3 Pending
NCI E-169-2021-0-CN-01 MIXED LINEAGE KINASE INHIBITORS AND METHODS OF USE CN National Stage Pending
NICHD E-200-2021-0-US-02 USE OF CARBOXYPEPTIDASE E/NEUROTROPHIC FACTOR-ALPHA1 TO TREAT NEURODEGENERATIVE DISEASE US National Stage 18/705,869 Pending
NIAID E-066-2014-0-US-28 STABILIZED INFLUENZA HEMAGGLUTININ STEM REGION TRIMERS AND USES THEREOF US DIV 18/648,190 Pending
NCI E-017-2017-0-US-11 BICISTRONIC CHIMERIC ANTIGEN RECEPTORS AND THEIR USES US CON 18/644,724 Pending
OD E-120-2021-0-US-02 PREDICTION OF TRANSFORMATIVE BREAKTHROUGHS IN RESEARCH US National Stage 18/703,175 Pending
NCI E-068-2018-0-CN-01 TETHERED INTERLEUKIN-15 AND INTERLEUKIN-21 CN DIV 202410477974.2 Pending
NIAID E-234-2016-1-US-05 PREFUSION CORONAVIRUS SPIKE PROTEINS AND THEIR USE US CON 18/638,334 Pending
NCI E-181-2017-0-MX-01 HLA CLASS II-RESTRICTED T CELL RECEPTORS AGAINST MUTATED RAS MX DIV MX/a/2024/004610 Pending
NCI E-003-2022-0-US-02 AUTOMATIC SYSTEM AND METHOD FOR TISSUE SECTIONING, STAINING, AND SCANNING US National Stage 18/700,977 Pending
NCATS E-172-2021-0-KR-01 SYNTHETIC HUMANIZED LLAMA NANOBODY LIBRARY AND USE THEREOF TO IDENTIFY SARS-COV-2 NEUTRALIZING ANTIBODIES KR National Stage 10-2024-7012300 Pending
NIMH E-070-2023-0-PC-01 SYSTEMS AND METHODS FOR MULTICHANNEL INDIVIDUALIZED STIMULATION THERAPY PCT PCT PCT/US2024/023876 Pending
NCI E-053-2019-0-CN-11 GENETICALLY MODIFIED HEMATOPOIETIC STEM AND PROGENITOR CELLS (HSPCs) AND MESENCHYMAL CELLS AS A PLATFORM TO REDUCE OR PREVENT METASTASIS, TREAT AUTOIMMUNE AND INFLAMMATORY DISORDERS, AND REBALANCE THE IMMUNE MILIEU AND DYSREGULATED NICHES CN DIV 202410413639.6 Pending
NHGRI E-134-2023-0-PC-01 SYNTHETIC MMAB GENES AND AAV VECTORS TO TREAT COBALAMIN B DEFICIENCY PCT PCT PCT/US2024/023432 Pending
NIAID E-160-2021-0-US-02 AUGMENTATION OF INNATE AND ADAPTIVE IMMUNITY BY INHIBITION OF INTERACTION OF LILRBS WITH MHC-1 US National Stage 18/699,057 Pending
NIA E-207-2021-0-US-02 COMPOUNDS FOR TREATING OR PREVENTING ALZHEIMER'S DISEASE US CIP 18/627,191 Pending
NINDS E-061-2023-0-PC-01 SYSTEMS AND METHODS FOR PATTERNED MULTI-SLICE EXCITATION IN MAGNETIC RESONANCE IMAGING PCT PCT PCT/US2024/022852 Pending
NCI E-280-2016-0-US-02 METHODS OF PREPARING AN ISOLATED POPULATION OF DENDRITIC CELLS AND METHODS OF TREATING CANCER USING SAME US CON 18/623,529 Pending
NICHD E-151-2021-0-US-02 NUCLEAR MAGNETIC RESONANCE METHODS OF DETERMINING HOMEOSTATIC
PERTURBATIONS 		US National Stage 18/697,168 Pending
NCI E-136-2023-0-PC-01 ALLOSTERIC INHIBITORS OF THE PLK1 POLO BOX DOMAIN, PHARMACEUTICAL COMPOSITIONS, AND METHOD OF TREATING CANCER PCT PCT PCT/US2024/022328 Pending
NIAID E-154-2017-0-US-05 NEUTRALIZING ANTIBODIES TO EBOLA VIRUS GLYCOPROTEIN AND THEIR USE US CON 18/619,995 Pending
NCI E-133-2016-0-EP-12 FLT3-Specific Chimeric Antigen Receptors and Methods Using Same EP DIV 24167685.7 Pending
NCI E-169-2021-0-KR-01 MIXED LINEAGE KINASE INHIBITORS AND METHODS OF USE KR National Stage 10-2024-7010519 Pending
NIAID E-228-2016-1-KR-17 Stabilized Group 2 Influenza Hemagglutinin Stem Region Trimers and Uses Thereof KR DIV 10-2024-7010062 Pending
NCI E-054-2023-0-PC-01 T CELL RECEPTORS TARGETING Y220C OR R175H MUTATION IN P53 PCT PCT PCT/US2024/021425 Pending
NHLBI E-080-2023-0-PC-01 ENZYMATIC RADIOSYNTHESIS OF DEOXY-[18F] FLUOROCELLOBIOSE AND DEOXY-[18F]
FLUOROCELLOTRIOSE 		PCT PCT PCT/US2024/021440 Pending
NIAID E-060-2015-0-US-18 NOVEL MULTIVALENT NANOPARTICLE-BASED VACCINES US DIV 18/615,895 Pending
NIAID E-270-2015-0-US-06 SELF-ASSEMBLING INSECT FERRITIN NANOPARTICLES US CON 18/615,011 Pending
NCATS E-172-2021-0-EP-01 SYNTHETIC HUMANIZED LLAMA NANOBODY LIBRARY AND USE THEREOF TO IDENTIFY SARS-COV-2 NEUTRALIZING ANTIBODIES EP National Stage 22782640.1 Pending
NHLBI E-146-2023-0-US-01 ANTIBODIES TARGETING CELL SURFACE DEPOSITED COMPLEMENT PROTEIN C3d AND USE THEREOF US ORD 18/610,978 Pending
NHLBI E-188-2021-0-IL-01 ANTI-CMPL DIVALENT SCFV AND USES THEREOF IL National Stage 311590 Pending
NCI E-169-2021-0-EP-01 MIXED LINEAGE KINASE INHIBITORS AND METHODS OF USE EP National Stage 22777538.4 Pending
NCATS E-172-2021-0-US-02 SYNTHETIC HUMANIZED LLAMA NANOBODY LIBRARY AND USE THEREOF TO IDENTIFY
SARS-COV-2 NEUTRALIZING ANTIBODIES 		US National Stage 18/692,570 Pending
NIAID E-052-2017-4-HK-02 Trispecific And/or Trivalent Binding Proteins For Prevention Or Treatment Of HIV Infection HK CN 42024088832.1 Pending
NIDCR E-094-2023-0-PCT-02 METHODS FOR PRODUCING STABLE HUMAN CHONDROCYTES AND THEIR USE PCT PCT PCT/US2024/020102 Pending
NCATS E-041-2021-3-PC-01 Combinations of Retinaldehyde Dehydrogenase 1 (RALDH1) Inhibitors and Immunostimulators and Methods Using Same PCT PCT PCT/US2024/020160 Pending
NCATS E-172-2021-0-JP-01 SYNTHETIC HUMANIZED LLAMA NANOBODY LIBRARY AND USE THEREOF TO IDENTIFY SARS-COV-2 NEUTRALIZING ANTIBODIES JP National Stage 2024-516630 Pending
NCI E-190-2014-0-US-02 VIRUS-LIKE PARTICLE CONJUGATES FOR DIAGNOSIS AND TREATMENT OF TUMORS US CON 18/605,198 Pending
NCATS E-172-2021-0-CA-01 SYNTHETIC HUMANIZED LLAMA NANOBODY LIBRARY AND USE THEREOF TO IDENTIFY SARS-COV-2 NEUTRALIZING ANTIBODIES CA National Stage 3232223 Pending
NCATS E-172-2021-0-AU-01 SYNTHETIC HUMANIZED LLAMA NANOBODY LIBRARY AND USE THEREOF TO IDENTIFY SARS-COV-2 NEUTRALIZING ANTIBODIES AU National Stage 2022345251 Pending
NICHD E-198-2022-0-PC-01 SYSTEM AND PROTOCOL FOR MONITORING PREGNANCY HEALTH PCT PCT PCT/US2024/019168 Pending
NHLBI E-188-2021-0-EP-01 ANTI-CMPL DIVALENT SCFV AND USES THEREOF EP National Stage 22813001.9 Pending
NEI E-194-2021-0-EP-06 Systems and Methods to Automatically Detect Ellipsoid Zone Loss in SD-OCT Imaging EP National Stage 22789416.9 Pending
NEI E-194-2021-0-US-05 Systems and Methods to Automatically Detect Ellipsoid Zone Loss in SD-OCT Imaging US National Stage 18/690,130 Pending
NIDA E-036-2023-0-PCT-01 DUAL-TARGETED OPIOID AND DOPAMINE D3 RECEPTORS LIGANDS PREPARATION AND USE THEREOF PCT PCT PCT/US2024/018704 Pending
NIBIB E-168-2021-2-JP-01 SYSTEMS AND METHODS FOR THREE-DIMENSIONAL STRUCTURED ILLUMINATION MICROSCOPY WITH ISOTROPIC SPATIAL RESOLUTION IMPROVEMENT OF AXIAL RESOLUTION IN 3D SIM VIA OPTICAL AND COMPUTATIONAL MEANS JP National Stage 2024-514683 Pending
NICHD E-200-2021-0-AU-01 USE OF CARBOXYPEPTIDASE E/NEUROTROPHIC FACTOR-ALPHA1 TO TREAT NEURODEGENERATIVE DISEASE AU National Stage 2022379620 Pending
NHLBI E-188-2021-0-US-02 ANTI-CMPL DIVALENT SCFV AND USES THEREOF US National Stage 18/688,899 Pending
NCATS E-095-2018-0-CN-01 QUINOLINE COMPOUNDS AND THEIR PREPARATION AND USE AS ANTIMALARIAL AGENTS CN DIV 202410240987.8 Pending
NICHD E-200-2021-0-CA-01 USE OF CARBOXYPEPTIDASE E/NEUROTROPHIC FACTOR-ALPHA1 TO TREAT NEURODEGENERATIVE DISEASE CA National Stage 3231009 Pending