Remotely Monitored Mouse Feeding Experimentation Device


How much does a mouse eat per day? If a researcher is conducting dietary studies, the answer is very important. For instance, obesity studies require accurate measures of feeding. Existing automated methods for taking feeding measurements are expensive and use specialized caging that is not compatible with typical vivarium colony racks. As a result, many researchers simply weigh food each day or two to determine how much food the mice ate. This is time-consuming, can be error prone, and provides a low temporal resolution view of feeding.

To address this need, a compact, 3D printed, electronic, feeding experimentation device has been developed. When the mouse takes a pellet, the device sends a timestamp via WiFi to a computer and dispenses another pellet. Multiple mice in a single cage can be identified with an RFID chip and individually monitored. In this way, a record of every pellet eaten by each mouse can be retrieved at the end of an experiment. This permits high-resolution views (# of meals, size of each meal) of feeding over long durations, without any specialized caging but with a reduction in researcher's hands-on time.

Potential Commercial Applications: Competitive Advantages:
  • Mouse diet experiments
  • Behavior - food reward training
  • Mouse health monitoring in other experiments
  • May be adapted for other small rodents
 
  • Small size, suitable for standard vivarium housing.
  • Electronic monitoring reduces need for personnel to monitor feeding behavior.
  • Can track multiple mice in a single cage.
  • Less-costly solution.
  • The same device can be used as for operant conditioning experiments.


Inventors:

Alexxai Kravitz (NIDDK)  ➽ more inventions...

Katrina Nguyen (NIDDK)  ➽ more inventions...


Intellectual Property:
This technology is not patented. Instructions for 3D printing, parts list, and assembly of components are available from contact below.

Publications:
Devarakonda K, et al. PMID 26019006

Collaboration Opportunity:

The NIH is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize Remotely Monitored Mouse Feeding Experimentation Device. For collaboration opportunities, please contact Marguerite J. Miller at Marguerite.Miller@nih.gov or 301-496-9003.


Licensing Contact:
Betty Tong, Ph.D.
Email: tongb@niddk.nih.gov
Phone: 301-451-7836

OTT Reference No: E-209-2015-0
Updated: Jul 26, 2016