cDNA for Murine PEDF


This technology is a cDNA, obtained from mouse liver, which encodes the open reading frame of the murine homolog of pigment epithelium-derived factor (mPEDF). PEDF is a serpin protein that has not been demonstrated to have serine protease activity in a physiological setting but which exhibits diverse biologic properties including neurotrophic activity and anti-angiogenic activity. The mPEDF cDNA may be used to study PEDF function and may be particularly useful in research applications comparing mPEDF to hPEDF. The cDNA, provided as a plasmid designated pMOU12A, can be readily inserted into an expression vector.

Inventors:

Ignacio Rodriguez (NEI)  ➽ more inventions...

Vijay Singh (NEI)  ➽ more inventions...

Gerald Chader (NEI)  ➽ more inventions...


Intellectual Property:
Research Tool -- patent prosecution is not being pursued for this technology

Publications:
Singh VK, et al. PMID 9565647

Licensing Contact:
Lynne Huang, Ph.D.
Email: yingling.huang@nih.gov
Phone: 240-276-5530

OTT Reference No: E-112-2004-0
Updated: May 10, 2018