Software System for Processing and Analysis of Multi-dimensional NMR Data


Available for licensing is a software system useful in applications involving nuclear magnetic resonance (NMR). The software system, called NMRPipe, is written in the C programming language, and makes use of the TCL/TK scripting environment. The system includes over 500 modules for processing and analyzing experimental data of one to four dimensions collected on NMR spectrometers. The system exploits the UNIX computer operating system facilities of pipelines and scripts to link modules in a highly flexible, user-definable manner. NMR is a widely used analytical method, applied to both solution and solid state samples. The information obtained from such data pertains to the structure, motion, and interactions of molecular systems, including proteins, nucleic acids, and organic molecules.

Potential Commercial Applications: Competitive Advantages:
  • Biomedical research for studying protein and nucleic acid structures and their interactions
  • Chemical applications involving synthesis, identification, or production of organic molecules
 


Development Stage:
  • The software is mature.
  • Binary executables of the software have been widely distributed, both to academic institutions as well as commercial organizations.
  • The software is under active development.
  • The software will be readily available upon request.


Inventors:

Frank Delaglio (NIDDK)  ➽ more inventions...


Intellectual Property:
Software - Patent protection is not being pursued for this technology.

Publications:
Kontaxis G, et al. PMID 15808217
Delaglio F, et al. PMID 11318630
Cornilescu G, et al. PMID 10212987
Delaglio F, et al. PMID 8520220

Collaboration Opportunity:

The National Institute of Diabetes and Digestive and Kidney Diseases is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize the NMRPipe software system. Please contact Marguerite Miller at 301-496-9003 or Frank Delaglio at frankde@niddk.nih.gov for more information.


Licensing Contact:
Betty Tong, Ph.D.
Email: tongb@mail.nih.gov
Phone:

OTT Reference No: E-076-2009/0
Updated: Sep 10, 2015