Device for Non-Surgical Tricuspid Valve Annuloplasty

This is a non-surgical tricuspid annuloplasty to treat functional tricuspid valve regurgitation, meaning regurgitation with intact valve leaflets. The device is delivered using novel catheter techniques into the pericardial space and positioned along the atrioventricular groove. A compression member is positioned along the tricuspid annular free wall and tension applied through a variably-applied tension element. In the best embodiment, the compression member has an M shaped portion with at least two inflection points between the segments of difference curvatures.

Potential Commercial Applications: Competitive Advantages:
  • Valvular heart disease
  • Tricuspid valve annuloplasty
  • Non-surgical catheter treatment of valve disease
  • Tricuspid valve

Development Stage:
  • Prototype
  • Pre-clinical
  • In vitro data available
  • In vivo data available (animal)

Related Invention(s):


Robert Lederman (NHLBI)  ➽ more inventions...

Toby Rogers (NHLBI)  ➽ more inventions...

Kanishka Ratnayaka (NHLBI)  ➽ more inventions...

Intellectual Property:
US Application No. 14/776,488
US Application No. 61/785,652
PCT Application No. PCT/US2014/025300

Collaboration Opportunity:

The NHLBI is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize technologies for functional tricuspid valve regurgitation. For collaboration opportunities, please contact Peg Koelble at

Licensing Contact:
Michael Shmilovich, J.D.
Phone: 301-435-5019

OTT Reference No: E-027-2013/0
Updated: Mar 15, 2017