Technology ID
E-213-2016-0

Murine Cell Models for Metastatic Squamous Cell Carcinoma

Linked ID
TAB-3015
Inventors
Carter Van Waes (NIDCD)
Zhong Chen (NIDCD)
Lead Inventors
Zhong Chen (NIDCD)
Co-Inventors
Carter Van Waes (NIDCD)
Applications
Research Materials
Therapeutic Areas
Oncology
ICs
NIDCD
Commercial Applications
  • Drug discovery for squamous cell carcinoma
  • Drug discovery for squamous cell carcinoma metastated to lung and lymph nodes
Two cell lines isolated from Pam 212 cells (SCC): Pam LY (lymph node metastasis) and Pam LU (lung metastasis) from metastated in vivo growth in mouse. These stably established cell lines exhibited higher potential to metastasize to lymph nodes and lungs, respectively, in mouse models than their parental Pam 212 cells.

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