Carter Van Waes (NIDCD)
Zhong Chen (NIDCD)
- Drug discovery for squamous cell carcinoma
- Drug discovery for squamous cell carcinoma metastated to lung and lymph nodes
Two cell lines isolated from Pam 212 cells (SCC): Pam LY (lymph node metastasis) and Pam LU (lung metastasis) from metastated in vivo growth in mouse. These stably established cell lines exhibited higher potential to metastasize to lymph nodes and lungs, respectively, in mouse models than their parental Pam 212 cells.