Technology ID
E-213-2013-0

Real-time PCR Assays for Human Bocavirus Detection and Diagnosis

Linked ID
TAB-2736
Inventors
Dean Erdman (CDC)
Teresa Peret (CDC)
Lead Inventors
Dean Erdman (CDC)
Co-Inventors
Teresa Peret (CDC)
Development Stages
Pre-Clinical (in vitro)
Development Status
In vitro data available
Applications
Diagnostics
Therapeutic Areas
Infectious Disease
ICs
CDC
Commercial Applications
  • Human bocavirus (HBoV) research tools
  • Respiratory illness diagnostics and research
  • Public health surveillance
  • Confirmation/diagnosis of HBoV infection
CDC researchers have developed a real-time PCR assay for the detection and viral-load quantitative estimations of human bocavirus (HBoV) from clinical specimens. At present, there have been few reports on the epidemiology, geographic distribution or clinical features of HBoV infection. Additionally, symptoms affiliated with bocavirus infections overlap with numerous other respiratory illnesses. This CDC assay provides sensitive, specific, and quantitative detection of HBoV in patients with respiratory illness by a method of real-time PCR targeting the HBoV NS1 and NP-1 genes. Use of this assay in conjunction with additional diagnostic methods and treatments should facilitate improved diagnosis and, subsequently, directed treatment and patient outcome.
Competitive Advantages
  • Specific and sensitive
  • Capable of rapid HBoV detection and distinction from alternate respiratory-illness linked pathogens
  • Superior to other HBoV detection methods in cost-efficiency, accuracy and quantitation of viral load

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