Technology ID
E-102-1999-0

HCV/BVDV Chimeric Genomes and Uses Thereof

Linked ID
TAB-489
Inventors
Jae-hwan Nam (NIAID)
Jens Bukh (NIAID)
Robert Purcell (NIAID)
Suzanne Emerson (NIAID)
Lead Inventors
Jae-hwan Nam (NIAID)
Co-Inventors
Jens Bukh (NIAID)
Robert Purcell (NIAID)
Suzanne Emerson (NIAID)
Applications
Research Materials
Therapeutic Areas
Infectious Disease
ICs
NIAID
The current invention provides nucleic acid sequences comprising chimeric viral genome of hepatitis C Virus (HCV) and bovine viral diarrhea viruses (BVDV). The chimeric viruses are produced by replacing the structural region or a structural gene of an infectious BVDV clone with the corresponding region or gene of an infectious HCV. It covers the use of these sequences and polypeptides encoded by all or part of the sequences in the development of vaccines and diagnostic assays for HCV and the development of screening assays for the identification of antiviral agents for HCV. {RefNo is 489 }

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