Technology ID
E-013-2017-0

Immortalized Stria Vascularis Cell Line SV-k1

Linked ID
TAB-3085
Inventors
Frederico Kalinec (NIDCD)
Gilda Canseco De Kalinec (NIDCD)
Lead Inventors
Gilda Canseco De Kalinec (NIDCD)
Co-Inventors
Frederico Kalinec (NIDCD)
Applications
Research Materials
ICs
NIDCD
Commercial Applications
  • Research
  • Hearing research
Available for nonexclusive licensing for research uses is the cell line, SV-k1, derived from the Organ of Corti. The line was developed from the stria vascularis, an organ localized on the lateral wall of the cochlea, adjacent to the Organ of Corti, containing cell populations specialized in the production of an endolymph very rich in K+ characteristic of the mammalian inner ear. SV-k1 cells express a set of biomarkers completely different of those expressed by OC-k3 cells, and are not sensitive to ototoxic drugs.

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