News and Events

Sep 9, 2019

In 2016, the National Cancer Institute (NCI) had initiated the Cancer Moonshot to accelerate cancer preventive, diagnostic and therapeutic innovations and medical products development; encourage collaborations and improve data sharing in the vast and dynamic field of cancer research. Cancer Moonshot was named in the memory of President John F. Kennedy’s inspirational speech in 1962 to win a space race against the Soviet Union to land the first man on the moon.

Aug 20, 2019

The National Cancer Institute (NCI) is building a national resource of cancer cell models derived from patients in NCI-sponsored clinical trials. This Patient-Derived Models Repository (PDMR) will contain patient-derived xenografts, primary and metastatic tumor cell cultures, blood specimens, cancer associated fibroblasts and organoids to boost public-private partnerships and academic drug discovery efforts.  The tissue samples from SCLC, pancreatic, bladder, head and neck, sarcoma, Non-Hodgkin Lymphoma and melanoma will also be stored and made publically available upon request.

Aug 14, 2019

more than 2 million people worldwide, multiple sclerosis is a disease for which there is no cure. The disease starts when the immune system attacks myelin, a protective coating that forms around nerve cells in a person’s brain and spinal cord, to produce a variety of initial symptoms, including blurred or double vision, problems with muscle strength, balance and coordination, and abnormal sensations. 

Jul 29, 2019

The mission of NIMH is to translate the understanding and treatment of mental illnesses through basic and clinical research leading to prevention, recovery and cure. Many pharmaceutical companies generally prefer to invest in more profitable disease areas. NIMH Intramural Research Program (IRP) initiated Translational Neuropsychopharmacology Task Force (TNTF) with expert scientists from the pharmaceutical industry and the NIH to recommend new project proposals for grant support by the NIMH IRP.

Jul 26, 2019

Over 300 million people worldwide are suffering from chronic depression. It is also one of the leading causes of disability in US and can be fatal as suicide kills more than 45,000 Americans annually. NIMH psychiatrist Dr. Carlos Zarate and collaborators discovered that a single intravenous dose of the “club drug” ketamine could produce significant antidepressant effects in 71% of the test subjects and remission in 29% patients with treatment-resistant depression (TRD) as compared with placebo.

Jul 1, 2019

Dr. Wiliam J. Pavan and his team at National Human Genome Research Institute (NHGRI) have established a novel diagnostic tool to predict time of onset for the rare neurodegenerative Niemann-Pick disease type C (NPC). The npc1 gene mutation leads to the lysosomal lipid storage disorder in neuronal tissue. Flowcytometric analysis of stained lysosomal structures in patient derived fibroblasts predicts the time of onset of the disease symptoms.

Apr 30, 2019

NCI research team, led by Dr. Mark Schiffman at Division of Cancer Epidemiology and Genetics (DCEG), is conducting a “Cervix Image Sharing Protocol (CISP)” study on artificial intelligence (AI) approach for better and low-cost screening and diagnosis of cervical cancer. TTC executed 14 Data Transfer Agreements (DTAs) with institutions worldwide for the development of algorithms to detect cervical precancers based on cervical images.

Apr 24, 2019

The European medical innovation journal, MedNous, featured a story in its March issue entitled “NCI and Industry: Moving Innovations from the Lab to Patients” authored by Michael Salgaller and Michele Newton. MedNous is both a print and online publication. NCI TTC is highlighted in the both the Letter to the Editor and in the feature story on pages 8 – 9.

Apr 5, 2019
NIH observed rare disease day on 28th February 2019 to build commitment in helping people with rare diseases through research at National Center for Advancing Translational Sciences (NCATS) and Clinical Center (CC). NCATS selected eleven honorable mentions and three winners from nearly fifty submissions to a challenge seeking creative ways to raise awareness about rare diseases and the need for expanded research, development of diagnostics and treatments and patient support.
Apr 5, 2019

Tick-borne diseases are emerging as a serious public health problem in the United States. Ticks transmit different infectious diseases including Lyme disease, Rocky Mountain spotted fever and babesiosis. According to CDC, there is more than 30,000 cases of Lyme disease reported each year in the U.S. while the actual incidence of Lyme disease is ten times greater. NIH is developing a strategic plan to accelerate research to develop new diagnostics and therapeutics to address the issue.