Technologies related to NHLBI

Potential Treatment for sickle-cell disease and thalassemia
Ref: E-200-2018-0 | Updated: Jan 17, 2019
Inner Curvature Charge Concentration Device for Tissue Laceration
Ref: E-064-2018-0 | Updated: May 21, 2018
Hybrid Computer Tomography Scanning System
Ref: E-175-2017-0 | Updated: Aug 23, 2017
Efficient mRNA-Based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7
Ref: E-036-2015-0 | Updated: May 17, 2017
T-cells Transduced with HLA A11 restricted CT-RCC HERV-E reactive TCR to Treat Patients with ccRCC
Ref: E-120-2016-0 | Updated: May 17, 2017
Capsid-Free AAV Vectors for Gene Delivery and Their Use for Gene Therapy
Ref: E-241-2010/0 | Updated: Oct 12, 2016
Enhanced Functionalization of Carbon Nanoparticles for Biomedical Applications
Ref: E-207-2016-0 | Updated: Oct 13, 2016
Alloreactive T Cell Depletion Method For Preventing Graft-Versus-Host Disease
Ref: E-125-2015-0 | Updated: May 14, 2018
Software for Fully Automating Myocardial Perfusion Quantification
Ref: E-097-2016/0 | Updated: Mar 3, 2016
Fluorescent Nanodiamonds as Fiducial Markers for Microscopy
Ref: E-217-2015-0 | Updated: Jan 14, 2016
Three-Dimensional Curved Catheter for Right Atrial Appendage Traversal
Ref: E-078-2015/0 | Updated: Sep 9, 2015
Genome Wide DNase I Hypersensitive Sites Detection in Formalin-Fixed Paraffin-Embedded Single Cells
Ref: E-254-2014-0 | Updated: Aug 17, 2015
Modified AAV5 Vectors for Enhanced Transduction and Reduced Antibody Neutralization
Ref: E-097-2015-0 | Updated: May 18, 2018
A Novel Adeno-Associated Virus for Gene Therapy
Ref: E-175-2015-0 | Updated: Nov 1, 2017
Device for Selective Partitioning of Frozen Cellular Products
Ref: E-173-2009/0 | Updated: Jun 29, 2015
A Novel Therapeutic Vector for Hemoglobin Disorders
Ref: E-165-2014-0 | Updated: Sep 21, 2015
Highly Sensitive Tethered-Bead Immune Sandwich Assay
Ref: E-188-2014/0 | Updated: Jan 13, 2015
A Novel X-ray Grating to Enhance Phase Contrast Imaging
Ref: E-114-2013-0 | Updated: May 18, 2018
A Novel Demodulation System in X-ray Imaging
Ref: E-113-2013-0 | Updated: May 18, 2018
Treatment of Chronic Kidney Disease with Synthetic Amphipathic Peptides
Ref: E-743-2013/0 | Updated: Jun 2, 2014
Real Time Medical Image Processing Using Cloud Computing
Ref: E-074-2014/0 | Updated: Jan 4, 2016
Human iPSC-Derived Mesodermal Precursor Cells and Differentiated Cells
Ref: E-342-2013-0 | Updated: May 14, 2018
Improved Culture Medium for Stem Cell Maintenance and Differentiation
Ref: E-089-2013-0 | Updated: Feb 6, 2014
AAV-Aquaporin-1 Gene Therapy for Sjogren's Syndrome
Ref: E-139-2011/1 | Updated: Dec 14, 2016
Device for Vascular Dilation
Ref: E-759-2013/0 | Updated: Dec 3, 2013
AAV-Aquaporin-1 Gene Therapy for Sjogren's Syndrome
Ref: E-139-2011-1 | Updated: Dec 14, 2016
Aortic Access from Vena Cava for Large Caliber Transcatheter Cardiovascular Interventions
Ref: E-553-2013/0 | Updated: Sep 10, 2013
MRI Scanner Bore Covering
Ref: E-026-2013/0 | Updated: Aug 6, 2013
Device for Non-Surgical Tricuspid Valve Annuloplasty
Ref: E-027-2013/0 | Updated: Mar 15, 2017
Encircling Suture Delivery System
Ref: E-115-2013/0 | Updated: Mar 15, 2017
Intra-bone Drug Delivery Device and Method
Ref: E-165-2012/0 | Updated: Feb 19, 2015
Induced Pluripotent Stem Cells Generated Using Lentivirus-based Reprogramming
Ref: E-274-2012-0 | Updated: May 7, 2013
Parvovirus B19 Vaccine
Ref: E-286-1988-1 | Updated: May 7, 2013
SIRT2 Inhibitors as Novel Therapeutics for Myocardial Infarction and Ischemic Stroke and to Prevent Necrosis
Ref: E-003-2013-0 | Updated: May 9, 2018
Axon Regeneration After Brain or Spinal Cord Injury
Ref: E-214-2012-0 | Updated: Nov 21, 2012
Endothelial Cell Line to Study Prevention of Atherosclerosis
Ref: E-149-2012-0 | Updated: Jun 13, 2012
Mouse Model of STAT5 for the Drug Screen and the Research of Cancer and Autoimmunity
Ref: E-080-2011-0 | Updated: Jun 13, 2012
Treatment of Viral Infection by Blocking Interleukin-21
Ref: E-017-2012-0 | Updated: Jun 6, 2012
Multilayer X-Ray Transmission Grating Array for Phase-Contrast Imaging and Tomography
Ref: E-207-2011/0 | Updated: Sep 9, 2015
Transgenic Human Interleukin-21 Mouse Model
Ref: E-231-2010-0 | Updated: Jan 18, 2012
Transgenic Mice Expressing Human Arginase II Gene in Endothelium: Useful for Studying Atherosclerosis and Other Vasculopathies
Ref: E-255-2010-0 | Updated: Aug 30, 2011
Mouse Model for Cerebral Cavernous Malformation, an Inherited Brain Disorder
Ref: E-158-2011/0 | Updated: Jun 15, 2011
Methods and Devices for Transcatheter Cerclage Annuloplasty
Ref: E-108-2010/0 | Updated: May 25, 2011
Single Channel MRI Guidewire
Ref: E-274-2010/0 | Updated: Mar 4, 2011
Active Adaptive Detuning Systems to Improve Safety of Interventional Devices
Ref: E-114-2010/0 | Updated: Mar 4, 2011
A Computer Program to Predict Optimal Sites on Protein Sequences for Production of Peptide-Directed Antibodies (NHLBI AbDesigner)
Ref: E-251-2010-0 | Updated: May 15, 2018
Novel Therapeutic Compounds for Treatment of Cancer and Immune Disorders
Ref: E-291-2009-0 | Updated: Nov 26, 2010
Superresolution Microscopy via Azicon Beam Polarization Devices
Ref: E-251-2009/0 | Updated: Aug 31, 2010
Parvovirus B19 Codon Optimized Structural Proteins for Vaccine and Diagnostic Applications
Ref: E-011-2010-0 | Updated: Apr 30, 2012
Erythroid Progenitor Cell Line for Hematological Disease Applications
Ref: E-151-2010-0 | Updated: Feb 28, 2011
Reversible SNAP-Tag and CLIP-Tag Ligands for Live Cell Imaging
Ref: E-057-2010/0 | Updated: Apr 20, 2010
Composite Probes and Use Thereof in Super Resolution Microscopy
Ref: E-253-2009/0 | Updated: Mar 21, 2013
A Method of Reducing Cholesterol Biosynthesis with Specific MicroRNAs
Ref: E-142-2009/0 | Updated: Jun 16, 2010
Defensin-Based Therapeutics for the Treatment of Pulmonary Disease
Ref: E-243-2009-0 | Updated: Jun 14, 2010
Signal-to-Noise Enhancement in Imaging Applications Using a Time-Series of Images
Ref: E-292-2009/0 | Updated: Sep 10, 2015
Therapeutic Peptide Treatment for Dyslipidemic and Vascular Disorders
Ref: E-138-2008-0 | Updated: Aug 8, 2016
A Locking Device for Permanently Securing Surgical Suture Loops
Ref: E-048-2009/0 | Updated: Jul 3, 2009
Self-Expanding Stent for Valve Replacement
Ref: E-337-2008-0 | Updated: May 17, 2018
Polyclonal Antibodies to the Kidney Protein Sodium-Hydrogen Exchanger 3 (NHE3)
Ref: E-253-2008-0 | Updated: May 5, 2009
Polyclonal Antibodies to Thiazide-Sensitive Sodium-Chloride Cotransporter (NCC)
Ref: E-254-2008-0 | Updated: May 5, 2009
Polyclonal Antibodies to NKCC2, a Kidney-Specific Member of the Cation Chloride Co-transporter Family, SLC12A1
Ref: E-255-2008-0 | Updated: May 5, 2009
Polyclonal Antibodies to the Kidney Protein Urea Transporter 1 (UTA1)
Ref: E-268-2008-0 | Updated: May 5, 2009
Active Guidewire Visualization Device and System for MRI Guided Interventions
Ref: E-209-2007/0 | Updated: Sep 1, 2008
Mapping Internal and Bulk Motion of an Object with Phase Labeling in Magnetic Resonance Imaging
Ref: E-234-1999/3 | Updated: Sep 16, 2015
Nitrite and Nitrite-Methemoglobin Therapy to Detoxify Stroma-Free Hemoglobin Based Blood Substitutes
Ref: E-259-2007-0 | Updated: Sep 23, 2015
Active MRI Compatible and Visible iMRI Catheter
Ref: E-298-2005/0 | Updated: Sep 15, 2015
ApoA-1 Mimetic Peptides Promoting Lipid Efflux from Cells for Treatment of Vascular Disorders
Ref: E-114-2004-0 | Updated: Nov 29, 2016
Eeyarestatins: Novel Deubiquitination Inhibitors for the Treatment of Drug-Resistant Cancers
Ref: E-208-2007-0 | Updated: Jun 14, 2010
Aquaporin 2 Polyclonal Antibodies
Ref: E-045-2008-0 | Updated: Dec 1, 2007
Novel Roles of a DNA Repair Protein, DNA-PKcs, in Obesity, Neurological Function, and Aging
Ref: E-068-2007/0 | Updated: Sep 2, 2009
Method for Inducing T-Cell Proliferation
Ref: E-104-2004/1 | Updated: Sep 15, 2015
Rapid Motion Perception MRI Navigator Method
Ref: E-164-2002/0 | Updated: Sep 15, 2015
Probe Set Global Optimization
Ref: E-332-2005/0 | Updated: Aug 1, 2007
Device and Method for Protecting Against Coronary Artery Compression During Transcatheter Mitral Valve Annuloplasty
Ref: E-249-2006/0 | Updated: Aug 1, 2007
Device and Method for Protecting Against Coronary Artery Compression During Transcatheter Mitral Valve Annuloplasty
Ref: E-249-2006-0 | Updated: Aug 1, 2007
Endotracheal Tube Using Unique Leak Hole to Lower Dead Space
Ref: E-269-2001/0 | Updated: Jun 1, 2007
Total Emission Detection System for Multi-Photon Microscopy
Ref: E-257-2005-0 | Updated: May 1, 2018
Enriched Natural Killer Cells for Adoptive Infusion Cancer Therapy
Ref: E-183-2004-1 | Updated: Sep 30, 2010
Method for Producing Significant Amounts of B19 Virus for Development of Killed or Attenuated Vaccines
Ref: E-188-2006-0 | Updated: Apr 21, 2016
ARH3, a Therapeutic Target for Cancer, Ischemia, and Inflammation
Ref: E-347-2004-1 | Updated: Jun 1, 2010
Method for Improved Phase Contrast MRI Resolution
Ref: E-134-2005/0 | Updated: Sep 15, 2015
Agonist Epitopes for Renal Cell Carcinoma
Ref: E-122-2006/0 | Updated: Jun 14, 2010
Agonist Epitopes for Renal Cell Carcinoma
Ref: E-122-2006-0 | Updated: Jun 14, 2010
A Novel MRI Adiabatic T2 Preparation Sequence with Reduced B1 Sensitivity
Ref: E-073-2005/0 | Updated: Apr 1, 2006
Live Tissue Imaging Gel
Ref: E-328-2005/0 | Updated: Apr 1, 2006
Peptides for Treatment of Tumor Necrosis Factor alpha Mediated Inflammatory Disease
Ref: E-208-2003-0 | Updated: Sep 28, 2012
AAV5 Vector and Uses Thereof
Ref: E-127-1998-0 | Updated: May 9, 2018
Variable Curve Catheter
Ref: E-035-2003/0 | Updated: Apr 20, 2010
Cannula for Pressure Mediated Drug Delivery
Ref: E-196-1998/2 | Updated: Mar 1, 2005
Tryptophan as a Functional Replacement for ADP-ribose-arginine in Recombinant Proteins
Ref: E-160-2002-0 | Updated: Mar 1, 2005
Anti-Proliferative Activity of an Unexpected mTOR Kinase Inhibitor
Ref: E-259-2003-0 | Updated: Aug 1, 2012
AAV4 Vector and Uses Thereof
Ref: E-071-2000-0 | Updated: May 9, 2018
AAV5 Vector for Transducing Brain Cells and Lung Cells
Ref: E-072-2000-0 | Updated: May 9, 2018
Methods for Diagnosis of Atherosclerosis
Ref: E-276-2004-2 | Updated: Jul 11, 2012
Infectious Clone of Human Parvovirus B19 and Methods of Use
Ref: E-178-2004-0 | Updated: Nov 1, 2004
Production of Adeno-Associated Viruses in Insect Cells
Ref: E-325-2001-1 | Updated: May 9, 2018
Novel Method of Fat Suppression in Steady State Free Precession (SSFP) Based Magnetic Resonance Imaging (MRI)
Ref: E-237-2003/0 | Updated: Sep 15, 2015
IL-21 Critically Regulates Immunoglobulin Production
Ref: E-211-2002/0 | Updated: May 1, 2004
Contrast Agent Enhancement of Chemical Exchange Dependent Saturation Transfer (CEDST) MRI
Ref: E-240-1998/0 | Updated: May 1, 2004
Particles for Imaging Cells
Ref: E-185-2002/0 | Updated: Dec 1, 2003


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