Technology Bundle ID: TAB-2938

Monoclonal Antibodies to the HIV-1 Core Protein p24

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Primary Inventors: 
Timothy Granade (CDC)
Chou-Pong Pau (CDC), Dennis Bagarozzi (CDC), Jason Goldstein (CDC), Sherry Owen (CDC), Shon Nguyen (CDC), Susan Wells (CDC)
Development Stage: 
Development Status: 
  • In vitro data available
  • Prototype
Institute or Center: 

The core proteins of HIV-1 are secreted into the environment during replication in the human body. The detection of the core protein p24 (molecular mass of 24 kilodaltons) serves as an indicator of early HIV-1 infection, and assays detecting it have been available since the late 1980s. However, the development of a rapid assay for the detection of HIV-1 p24 has only recently become available. Monoclonal antibodies developed in our laboratory for research and development of a rapid HIV-1 p24 assay would provide large quantities of material at a much lower price than could be obtained in the commercial market.

  • Diagnostic assay for the detection of HIV-1
  • Research tool used to study HIV-1
  • Inexpensive antibodies to HIV-1 core proteins
  • Larger source of HIV-1 monoclonal antibodies


EIR Application

Research Tool - Patent protection is not being pursued for this technology.


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PMID 15542143
Miles SA, et al.
PMID 8419814
Schupbach J, Boni J.
PMID 8366170
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PMID 9665998
Workman S, et al.
PMID 19482361


May 19, 2015

Data Source: