Neglected Diseases

Neglected Diseases — HIV/AIDS

Technologies Available from NIH, Universities and Other Non-profit Organizations

JOHNS HOPKINS UNIVERSITY (JHU)
JHU 9363	Antiviral Therapy Using Viral Structural Protein-Enzyme Fusion Proteins
JHU 4478	New Inhibitor of HIV-1 Replication, Ubiquitin Like Protein ISG15
JHU 4477	The Amino Acid Noose of the Attachment Protein of Respiratory Syncytial Virus (RSV) Inhibits the Effects of the Endotoxin and the Innate Immune Response
JHU 4395	Single Cell Analysis of HIV Replication Capacity and Drug Resistance
JHU 4347	Use of Oxylipins and Bacterial Phytotoxins as Immunosuppressive and Anti-viral Agents*
JHU 4345	Use of Betacyclodextrins as Therapeutic Agents for the Treatment of Infectious Diseases
JHU 4343	Use of Betacyclodextrins For General Prophylaxis Against Contact Transmission of Viruses and Other Pathogens
JHU 4222	Suppression of HIV Replication and Prevention/Treatment of HIV-Associated Dementia
JHU 4052	Use of Immunophilin Ligands to Prevent Neurotoxicity Associated with Use of Nucleoside Analogue Reverse Transcriptase Inhibitors
JHU 3899	Inhibition of Retroelement Replication With Divalent Cations*
JHU 3890	Macaca Mulatta CCR8 cDNA
JHU 3712	LuSIV Cells: A Highly Sensitive Detection System for Infectious HIV and Related Retroviruses
JHU 3444	Neutralization of HIV-1 by Bacterial Toxins
JHU 3302	Use of Multivalent Chimeric Peptide-Loaded, MHC/lg Molecules to Detect, Activate or Suppress Antigen-Specific, T Cell-Dependent Immune Responses
JHU 3243	Monoclonal Antibodies (and Their Production) Against HIV and SIV Co-receptors: Chemokine Receptors
JHU 3002	Intervention in and Prevention of Epstein-Barr Virus Infection through Targeting of the EBNA2/CBF1 Interaction
JHU 1614	Antiviral Compositions and Methods of Use
JHU 1443	Compositions and Methods for Prevention of HIV Transmission Across Mucosal Surfaces
UNIVERSITY OF CALIFORNIA, OFFICE OF THE PRESIDENT (UCOP)
1992-319	A Marker for HIV Detection and Gene Expression
NATIONAL INSTITUTES OF HEALTH (NIH)
E-073-2004	Reduction of HIV-1 Replication by a Mutant Apolipoprotein B mRNA Editing Enzyme-Catalytic Polypeptide-like 3G (APOBEC3G)
E-041-2004	Codon-Optimization of the HIV-1 Vif Gene
E-039-2004	Peptide Inhibitors of HIV-1 Integrase Useful for the Treatment of Retroviral Infection and HIV
E-019-2004	Construction of Replication-Competent Chimeric Simian Immunodeficiency Virus (SIV) Human Immunodeficiency Virus Type 1 (HIV-1) Viruses that Replicate Using HIV-1 Reverse Transcriptase and Integrase (IN): A Model System for Development and Testing of Antiviral Agents for the Treatment of HIV-1 Infection
E-018-2004	Strand-Specific Amplification
E-356-2003	Chimeric HIV/SIV Polypeptide Trimers as HIV/AIDS Vaccine Candidates
E-335-2003	Mechanisms for Improving the Breadth of the Immune Response to Diverse Strains and Clades of HIV
E-316-2003	Immunoglobulins with Potent and Broad Antiviral (HIV) Activity Based on scFv Joined by Flexible Linker to Fc
E-265-2003	Methods for Inhibiting HIV and Other Viral Infections by Modulating Ceramide Metabolism
E-022-2003	Discovery of Novel Inhibitors of HIV-1 Integrase and/or RNase H That Can Be Used for the Treatment of Retroviral Infection Including AIDS
E-317-2001	Discovery of Novel Inhibitors of HIV-1 Integrase That Can Be Used for the Treatment of Retroviral Infection Including AIDS
E-193-2001	Single-Chain Antibody Fragment Protein Binding to HIV-1 Integrase
E-110-2001	A Plasmid for Expression of a More Soluble Form of HIV Integrase Protein in E. coli
E-036-1999	Thiazepine Inhibitors of HIV-1 Integrase
E-076-1999	Acetylated and Related Analogues of Chicoric Acid as HIV Integrase Inhibitors
E-061-1992	Anti-HIV Proteins GAP 31, DAP 30 and DAP 32 and Therapeutic Uses Thereof
E-190-1990	Plant Protein Useful for Treating Tumors and HIV Infection
* Some technologies have multiple potential uses.

Overview

African Trypanosomiasis (Sleeping Sickness)

Dengue Fever

General (Vaccines and Biotherapeutics)

Hepatitis B

HIV/AIDS

Intestinal Parasites

Leprosy

Lymphatic Filariasis (Elephantiasis)

Malaria

Rotavirus

Schistosomiasis

Tuberculosis

Visceral Leishmaniasis