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Top 20 Commercially Successful Inventions*

VACCINES AND THERAPEUTICS
Invention Description Inventor Rank
Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 Erickson et al. (NCI) (1)
HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins Lowy et al. (NCI) (2)
Monoclonal Antibody for Treatment of RSV Murphy et al. (NIAID) (3)
Proteosome Inhibitor for Treatment of Multiple Myeloma Gupta et al. (NCI) (4)
Nutritional Supplement to Treat Macular Degeneration Ferris et al. (NEI) (7)
Vaccinia Virus Vector Used in Biologicals/Vaccines Moss et al. (NIAID) (10)
AIDS Drug ddI Mitsuya et al. (NCI) (11)
Paclitaxel as a Cancer Treatment Wilson et al. (NCI) (12)
Radioimmunotherapy for Non-Hodgkin's Lymphoma Gansow et al. (NCI) (15)
Modified Cyclodextrin for enhanced Drug Uptake Pitha (NIA) (18)
Synthetic Thyrotropin as Adjuvant in Thyroid Cancer Wondisford et al. (NIDDK) (20)
DIAGNOSTICS
Invention Description Inventor Rank
Serological Detection of Antibodies to HIV-1 Gallo et al. (NCI) (6)
DNA Probe for Breast Cancer Diagnosis King et al. (NCI) (8)
Genoyping of HIV Protease Gene Oroszlan et al. (NCI) (9)
Diagnostic for Norwalk-like Virus Green et al. (NIAID) (16)
INSTRUMENTATION/DEVICES
Invention Description Inventor Rank
Paclitaxel-Eluting Coronary Stent System Kinsella et al. (NIA) (5)
Diffusion Tensor Magnetic Resonance Imaging Basser et al. (NICHD) (13)
Laser Capture Microdisection Liotta et al. (NCI) (19)
RESEARCH MATERIALS
Invention Description Inventor Rank
Neutrophil Chemotactic Factor (IL-8) Matsushima et al. (NCI) (14)
Purified Transforming Growth Factor Beta (TGF-beta) Sporn et al. (NCI) (17)

*for FY 2010, based on royalties on product sales


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