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Top 20 Commercially Successful Inventions*

VACCINES AND THERAPEUTICS
Invention Description Inventor Rank
HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins Lowy et al. (NCI) (1)
Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 Erickson et al. (NCI) (2)
Monoclonal Antibody for Treatment of RSV Murphy et al. (NIAID) (3)
Synthetic Thyrotropin as Adjuvant in Thyroid Cancer Wondisford et al. (NIDDK) (4)
Proteosome Inhibitor for Treatment of Multiple Myeloma Gupta (NCI) (5)
AIDS Drug ddI Mitsuya et al. (NCI) (7)
Nutritional Supplement to Treat Macular Degeneration Ferris et al. (NEI) (8)
Paclitaxel as a Cancer Treatment Wilson et al. (NCI) (11)
Vaccinia Virus Vector Used in Veterinary Biologicals/Vaccines Moss et al. (NIAID) (13)
Radioimmunotherapy for Non-Hodgkin's Lymphoma Gansow (NCI) (17)
DIAGNOSTICS
Invention Description Inventor Rank
Serological Detection of Antibodies to HIV-1 Gallo et al. (NCI) (9)
DNA Probe for Breast Cancer Diagnosis King et al. (NCI) (10)
Genoyping of HIV Protease Gene Oroszlan et al. (NCI) (14)
Norwalk Virus - IVD Product Green et al. (NIAID) (18)
INSTRUMENTATION/DEVICES
Invention Description Inventor Rank
Paclitaxel-Eluting Coronary Stent System Kinsella et al. (NIA) (6)
Diffusion Tensor Magnetic Resonance Imaging Basser et al. (NICHD) (12)
Laser Capture Microdisection Liotta et al. (NCI) (15)
Enhanced Magnetic Resonance Imaging Through Magnetization Transfer Balaban et al. (NHLBI) (16)
RESEARCH MATERIALS
Invention Description Inventor Rank
Purified Transforming Growth Factor Beta (TGF-beta) Sporn et al. (NCI) (19)
Neutrophil Chemotactic Factor (IL-8) Matsushima et al. (NCI) (20)

*for FY 2009, based on royalties on product sales


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