Licensing & Royalties >> Licensing Opportunities >> Technology Abstracts   Cancer - Diagnostics: Date Ref. No. Patent No. Title 5/10/2013 E-053-2013/0 A Diagnostic Kit for Assessing Exposure or Infection by the Koala Family of Retroviruses 4/23/2013 E-111-2013/0 Zirconium-89 PET Imaging Agent for Cancer 4/23/2013 E-020-2013/0 Urine-based Diagnostic Assay for the Early Detection of Cancer 4/11/2013 E-317-2004/1 7,785,565 Metal Chelators and Target-Moiety Complexes for Imaging 3/18/2013 E-236-2012/0 Single Domain Human Monoclonal Antibodies To Mesothelin for Treatment of Cancer 2/19/2013 E-135-2012/0 Benign Tissue or Malignant Tumors? Using CpG Dinucleotide Methylation Patterns to Diagnose Cancer in the Adrenal Glands and Adrenal Cortex 2/19/2013 E-198-2012/0 High-Affinity Rabbit Monoclonal Antibodies To Mesothelin for Treatment of Cancer 2/15/2013 E-021-2008/0 Monoclonal Antibody to a Specific Peptide-MHC Class II Complex 2/15/2013 E-119-2003/0 Mouse Monoclonal Antibodies to MAD1, a Human Spindle Assembly Checkpoint Protein for Maintaining Chromosomal Segregation 2/4/2013 E-029-2012/0 E-244-2010/0 Mutations in the G Protein Coupled Receptor (GPCR) Gene Family in Melanoma 1/8/2013 E-024-2009/0 Gene Signature for Predicting Solid Tumors Patient Prognosis 11/21/2012 E-256-1999/0 7,659,081 7,993,857 Methods for Measuring Adrenomedullin and Monitoring and Treating Adrenomedullin-mediated Diseases, Such as Diabetes and Cancer 11/16/2012 E-230-2012/0 A New Class, Now in Session: the First HLA Class II Restricted T Cell Receptor that Recognizes the Cancer Testis Antigen, MAGE-A3, Developed for Cancer Immunotherapy 11/1/2012 E-026-2011/0 Altered miRNA Expression as Diagnostics and Therapeutics for Adrenocortical Carcinomas 10/6/2012 E-177-2006/0 7,553,936 New Target for the Treatment of Cancer, Infectious Diseases, Cardiac Diseases, and Platelet-Associated Disorders 10/6/2012 E-073-2012/0 Antagonist of A3 Adenosine Receptor Fluorescent Probes for the Study of Diseases that Involve A3 Signaling 10/6/2012 E-078-2012/0 Chimeric Antigen Receptors that Recognize Mesothelin for Cancer Immunotherapy 8/28/2012 E-148-2011/0 Breakthrough Immunotherapy for Brain Cancer 8/17/2012 E-097-2009/0 Chimeric Anti-human ROR1 Monoclonal Antibodies 8/4/2012 E-269-2010/0 Synovial Sarcoma X Breakpoint-2 (SSX-2) Specific Human T Cell Receptors for Treating a Wide-Range of Cancers 8/4/2012 E-138-2001/0 7,618,789 Use of Semenogelin in the Diagnosis, Prognosis, and Treatment of Cancer 8/1/2012 E-194-2005/0 7,871,777 The Medusa™ Sequencer: A DNA or RNA Sequencing Machine the Size of a Molecule 8/1/2012 E-195-2005/0 E-195-2005/1 8,344,121 Nanoprobes for Detection or Modification of Molecules 8/1/2012 E-042-1998/0 6,897,018 7,534,565 DLC-1 Gene Deleted in Cancers 6/29/2012 E-013-2012/0 Methods for Selection of Cancer Patients and Predicting Efficacy of Combination Therapy with Histone Deacetylase (HDAC) and mTOR Inhibitors 6/1/2012 E-317-2008/0 Identification of Renal Cell Carcinoma Biomarkers 5/31/2012 E-261-2005/0 E-261-2005/1 E-261-2005/2 7,964,365 8.304,199 B2 Sensitive Antibody-based Assay for the Measurement of c-Met Concentration Shed in Bodily Fluids Useful in the Diagnosis and Prognosis of Cancer 5/9/2012 E-119-2011/0 Biomarker to Predict High-risk Clinical Outcomes for Colon, Lung, and Ovarian Cancers 4/30/2012 E-097-2012/0 Mouse Monoclonal Antibody Targeting Human NOX1, a Target for Cancer and Inflammation 4/30/2012 E-233-2011/0 Cell Line for Producing Furin That Can Cleave Papillomavirus L2, Toxins and Other Substrates 4/3/2012 E-178-2009/0 Glioblastoma Diagnostics and Therapeutics 3/29/2012 E-011-1998/0 6,849,417 7,442,543 7,776,607 Mammalian Selenoprotein Differentially Expressed in Tumor Cells 3/27/2012 E-205-2011/0 Novel Diagnostic, Prognostic and Therapeutic Biomarker for Hepatocellular Carcinoma 3/2/2012 E-175-2008/0 8,216,783 Over-expression and Mutation of a Tyrosine Kinase Receptor FGFR4 in Tumors 2/29/2012 E-149-2011/0 NOX5 Immunogenic Peptides and Monoclonal Antibodies for the Detection of Cancer and Inflammatory Responses 1/17/2012 E-252-2011/0 Enhancement of Cancer Imaging and Treatment with Somatostatin Analogs 12/2/2011 E-280-2010/0 Biomarkers for Cancer-Related Fatigue and Their Use in the Management of Such Fatigue (CRF) 11/18/2011 E-171-2011/0 DPEP1 and TPX2 as Prognostic Biomarkers for Pancreatic Ductal Adenocarcinoma 10/28/2011 E-266-2011/0 New non-HLA-A2 Restricted Human T Cell Receptors (TCRs) that Could be Used to Treat a Broader Cancer Patient Population Via TCR Adoptive Immunity 10/3/2011 E-096-2011/0 Tumor Markers for Potentially Predicting Outcome of Anti-angiogenesis Therapy 9/30/2011 E-094-1994/0 7,070,972 7,488,808 7,902,348 Janus Family Kinases (JAK) And Identification Of Immune Modulators 9/29/2011 E-287-2004/1 7,999,077 Monoclonal Antibodies to FCRL5 (CD307e/IRTA2/FcRH5) as Therapeutics and Diagnostics for B-cell Cancers 9/29/2011 E-086-2003/0 7,553,822 8,124,753 Potent Inhibitory RNAs for Non-Surgical Treatment of Salivary Gland Cancers 8/9/2011 E-173-2010/0 Immunocompetent Mouse Model for Tracking Cancer Progression 8/5/2011 E-013-2011/0 TRRAP and GRIN2A Mutations for the Diagnosis and Treatment of Melanoma 8/2/2011 E-056-2007/0 8,017,938 Microarray Binding Sensors Using Carbon Nanotube Transistors 8/2/2011 E-232-2009/0 Human Single-domain Antibodies (dAbs) Against Insulin-like Growth Factor 1 Receptor (IGF-1R) and Its Ligands 7/25/2011 E-130-2011/0 Monoclonal Antibodies to Glypican-3 Protein and Heparin Sulfate for Treatment of Cancer 7/21/2011 E-039-2011/0 Monoclonal Antibodies for Rare Diseases 7/5/2011 E-117-2011/0 E-174-2011/0 An Improved Anti-Mesothelin Immunotoxin for Treatment of Mesothelioma, Lung Cancer Ovarian Cancer and Pancreatic Cancer 6/17/2011 E-091-2009/0 Antibody and Immunotoxin Treatments for Mesothelin-expressing Cancers 6/1/2011 E-118-2009/0 Novel Diagnostic and Therapeutic Biomarkers for Squamous Cell Carcinomas 5/2/2011 E-191-2009/0 Akt-Ser473 Phosphorylation as a Marker for Predicting Taxane Chemotherapy Outcome 4/12/2011 E-281-2007/0 E-281-2007/1 Three-Dimensional Co-Culture Assay System for Angiogenesis and Metastasis 2/28/2011 E-236-2010/0 Versatile Melanoma Antigen Family A3 (MAGE-A3) Specific Human T Cell Receptors to Treat Cancer that also Recognize Other MAGE-A Antigen Superfamily Members 2/17/2011 E-005-2002/0 1497320 7,816,087 7,897,355 Gene Expressed in Prostate Cancer and Methods of Use 2/7/2011 E-234-2008/2 Method for Predicting and Detecting Tumor Metastasis 2/1/2011 E-163-2009/0 B-cell Surface Reactive Antibodies for the Treatment of B-Cell Chronic Lymphocytic Leukemia 9/30/2010 E-284-2008/0 Small-Molecule TSH Receptor Modulators for Diagnosis and Treatment of Thyroid Disease and Cancer 8/11/2010 E-314-2008/0 Inflammatory Genes and MicroRNA-21 as Biomarkers for Colon Cancer Prognosis 8/4/2010 E-086-2001/1 7,419,957 7,749,967 8,252,545 Novel Peptides to a Melanoma Antigen and Their Use in Diagnostic and Therapeutic Methods 8/2/2010 E-066-1998/0 6,485,925 6,893,835 6,911,203 7,056,693 7,183,071 Use of Anthrax Lethal Factor to Treat Cancer and Screening Methods for MAPK Kinase Protease Activity 6/16/2010 E-296-2004/0 Novel Form of Interleukin-15, Fc-IL-15, and Methods of Use 6/16/2010 E-086-2007/0 8,303,960 An Imaging Radiotracer for the Noninvasive Detection of HER2-positive Tumors 6/16/2010 E-092-2008/0 Novel Oligonucleotides for Treatment of Human Cancer 6/14/2010 E-122-2006/0 Agonist Epitopes for Renal Cell Carcinoma 6/14/2010 E-166-2007/0 Discovery of and Use of Fragments of DOC1 as Antiangiogenic and Antitumor Therapy 6/14/2010 E-089-2009/0 Immunogenic Tumor-associated Antigen SPANX-B for Selective Cancer Immunotherapy 6/14/2010 E-153-2008/0 Radioprotectants and Tumor Radiosensitizers Targeting Thrombospondin-1 and CD47 6/10/2010 E-062-1996/0 E-099-1996/0 E-154-1998/0 E-200-1990/3 E-200-1990/4 E-256-1998/0 E-259-1994/3 E-259-1994/4 E-260-1994/1 6,001,349 6,045,802 6,165,460 6,319,496 6,548,068 6,756,038 6,893,869 6,946,133 6,969,609 7,118,738 7,211,432 7,368,116 7,410,644 7,547,773 7,598,225 7,662,395 7,723,096 7,771,715 7,871,986 8,178,508 Enhanced T-cell Activation by Costimulation: An Effective Immunotherapy for Cancer and Infectious Diseases 6/7/2010 E-331-2008/0 E-331-2008/1 Fully-human Monoclonal Antibodies Against Human EphrinB2 and EphB4 for Use in the Study of Cancer Pathogenesis 3/1/2010 E-300-2008/0 Diagnostic Biomarker of Metastasis for Improved Clinical Management of Head and Neck Cancer 3/1/2010 E-216-2003/0 Mouse Lacking the Chemokine Receptor CX3CR1 1/22/2010 E-272-2008/0 Mutations of the ERBB4 Gene in Melanoma 1/22/2010 E-326-2007/0 Diagnostic Tool for Diagnosing Benign Versus Malignant Thyroid Lesions 1/22/2010 E-295-2001/0 Imaging of Extracellular Proteases in Cells Using Mutant Anthrax Toxin Protective Antigens 12/11/2009 E-106-2005/0 Identification of Colorectal Cancer Biomarkers by Serum Protein Profiling 12/2/2009 E-005-2010/0 Human Renal Cell Carcinoma (RCC) Cell Lines Derived from Surgically Removed Tumors 11/4/2009 E-248-2002/0 Methods and Compositions for the Diagnosis of Neuroendocrine Lung Cancer 10/12/2009 E-328-2007/0 Identification of Persons Likely to Benefit from Statin Mediated Cancer Prevention by Pharmacogenetics 8/11/2009 E-058-2009/0 Development of a New Carbohydrate Antibody to GalNac1-3Gal 7/2/2009 E-042-2009/0 Immunogenic Peptide from NGEP Protein for Developing Prostate Cancer Vaccines 5/28/2009 E-023-2009/0 Genomics-based Diagnostic Assay for Cancer 5/11/2009 E-304-2006/0 8,088,379 Enhanced Function of Gene Modified T-Cells: Identification of T-Cell Receptors (TCR) with Altered Amino Acid Sequence 5/5/2009 E-179-2008/0 Salcut-NH2: A Novel Target for Development of Anti-Tumorigenic, Anti-Angiogenic Therapeutics and Diagnostics 5/4/2009 E-154-2004/0 Creation and Characterization of Carcinogen-Altered Mouse Epidermal Cell Lines 5/4/2009 E-025-2009/0 Ratio Based Biomarkers for the Prediction of Cancer Survival 3/23/2009 E-314-2006/0 8,023,710 Increased Image Quality for Early Colon Polyp Detection 2/2/2009 E-215-2008/0 Prognostic Test for Breast Cancer Based on a 12 Gene Expression Signature 12/1/2008 E-283-2008/0 Method for Detection of Cancer Based on Spatial Genome Organization in the Cell Nucleus 11/1/2008 E-256-2008/0 Gene Expression Profiling for Prognosis of a Non-Hodgkin Lymphoma 10/1/2008 E-263-2006/1 Methods of Determining the Prognosis of an Adenocarcinoma 9/1/2008 E-139-1999/0 7,081,518 A Novel Recombinant Immunotoxin SS1P (anti-mesothelin dsFv-PE38): A Therapeutic Treatment for Lung Cancer and Other Mesothelin Expressing Cancers 9/1/2008 E-147-2008/0 Cyclized NGR Peptide for Tumor Targeting 8/1/2008 E-285-2006/2 8,440,411 New Tumor Endothelial Markers: Genes that Distinguish Physiological and Pathological Angiogenesis 8/1/2008 E-093-2007/0 Extracellular Matrix Gene Chips to Detect Metastatic Tumors 8/1/2008 E-062-1996/0 E-099-1996/0 E-154-1998/0 E-200-1990/3 E-200-1990/4 E-256-1998/0 E-259-1994/3 E-259-1994/4 E-260-1994/1 6,001,349 6,045,802 6,165,460 6,319,496 6,548,068 6,756,038 6,893,869 6,946,133 6,969,609 7,118,738 7,211,432 7,368,116 7,410,644 7,547,773 7,598,225 7,662,395 7,723,096 7,771,715 7,871,986 8,178,508 Enhanced T-cell Activation by Costimulation: A Potentially Novel Approach for the Prevention and/or Therapy of Cancer (Excluding Prostate Diseases and Melanoma) and for Infectious Diseases 8/1/2008 E-262-2000/0 E-262-2000/1 6,977,241 7,425,537 SH2 Domain Binding Inhibitors 7/1/2008 E-263-2004/0 7,892,738 A New Pot1 Variant Gene as a Diagnostic Biomarker for Hereditary Non-polyposis Colorectal Cancer 7/1/2008 E-071-2003/0 7,316,903 Rapid and Sensitive Detection of Nucleic Acid Sequence Variations 5/1/2008 E-080-2008/0 Human and Improved Murine Monoclonal Antibodies Against CD22 5/1/2008 E-079-2008/0 8,357,783 Human Monoclonal Antibody Against Mesothelin 5/1/2008 E-192-2007/0 A Molecular Grading System for Ductal Carcinoma In Situ (DCIS) of the Breast: A New Molecular Diagnostics to Determine Disease Stages of DCIS 2/1/2008 E-137-2006/0 E-137-2006/1 7,985,561 Manganese Superoxide Dismutase VAL16ALA Polymorphism Predicts Resistance to Doxorubicin Cancer Therapy 2/1/2008 E-186-2007/2 8,394,411 Papilloma Pseudovirus for Detection and Therapy of Tumors 1/1/2008 E-084-1991/1 6,274,134 Antibodies and Polypeptides Specific to AAMP-1: Diagnostic and Therapeutic Uses Thereof 12/1/2007 E-194-2007/0 Tri-functional Imaging Agent for Monoclonal Antibody Tumor-Targeted Imaging 12/1/2007 E-157-2007/0 Nanoparticles For Imaging: Targeted Nanoparticles That Can Be Imaged Through Magnetic Resonance, Optical, And Radioisotope Imaging 11/1/2007 E-061-2007/0 Diagnostic Ovarian Cancer Biomarkers 11/1/2007 E-139-1999/0 7,081,518 A Clinically Proven Therapeutic Treatment and Diagnostic Tool for Mesothelin Expressing Cancers: A Novel Recombinant Immunotoxin SS1P (anti-mesothelin dsFv-PE38) 11/1/2007 E-083-2007/0 SLCO1B3 Genotyping to Predict a Survival Prognosis of Prostate Cancer 11/1/2007 E-231-1995/3 E-232-1995/0 E-232-1995/1 5,556,763 5,658,744 5,965,366 A New Method for Determining Level of Immunosuppression in Humans 9/1/2007 E-226-2006/0 8,288,530 New Synthetic Variants of 2-(4-isothiocyanatobenzyl)-6-methyldiethylenetriamine Pentaacetic Acid (1B4M-DTPA): Novel Macromolecular MRI Contrast Agents 9/1/2007 E-272-1998/0 6,790,948 7,431,926 7,919,590 8,206,937 Tumor Suppressor Genes 8/1/2007 E-028-1999/0 7,399,827 Diagnostic and Therapeutic Methods of Detecting and Treating Cancers of Reproductive Tissues 8/1/2007 E-081-2004/2 7,838,305 Serum Autoantibody for Cancer Diagnostics 7/1/2007 E-118-2005/0 A Gene Therapy to Treat Lung Cancer 6/1/2007 E-117-2006/0 8,206,933 8,440,415 Diagnostic and Therapeutic Use of Brother of the Regulator of Imprinted Sites (BORIS) Alternative Splice Forms 6/1/2007 E-060-2007/0 A Gene Expression Profile that Predicts Ovarian Cancer Patient Response to Chemotherapy 5/1/2007 E-082-2005/0 E-082-2005/2 Sipa-Gene and Sipa-1 Inhibitor for the Diagnosis and Treatment of Metastatic Cancer 5/1/2007 E-018-2005/2 8,110,352 Diagnosing and Treating Cancer Using beta-Catenin Splice Variants 5/1/2007 E-070-2005/0 8,242,160 Inhibitors of Ubiquitin E1 5/1/2007 D-001-1996/1 D-001-2006/0 D-003-1992/3 D-003-1992/4 D-004-1992/0 D-004-1992/1 E-259-1998/2 5,877,291 5,892,020 5,993,813 6,051,225 6,071,515 6,207,815 6,329,507 6,348,581 6,641,999 6,737,060 6,737,061 6,752,990 6,753,152 6,753,420 6,818,749 628078 7,256,004 7,763,719 8,029,788 Humanized Anti-Carcinoma CC49 Monoclonal Antibodies 3/1/2007 E-290-2000/0 7,078,176 A Novel, Clinically Validated, Efficient and Non-Invasive In Vitro Diagnostic and Prognostic Test for Cancer 1/1/2007 E-132-2006/0 E-132-2006/1 E-132-2006/2 7,985,548 A New Method for Improving the Therapeutic Efficacy of L-Asparaginase in Multiple Types of Cancer 1/1/2007 E-293-2006/0 Megakaryocyte Potentiation Factor as a New Serum Tumor Marker for Mesothelioma 12/1/2006 E-125-2006/1 Extracellular Matrix/Metastasis Modifier Genes as a Method for Characterization and Prevention of Metastatic Tumor 10/1/2006 E-027-2006/0 7,847,078 PDE11A as a Novel Therapeutic Target for Inherited Form of Cushing Syndrome and Endocrine Tumors 9/1/2006 E-207-2006/0 Novel Monoclonal Antibody Microarray 9/1/2006 E-265-1997/0 7,084,239 Cancer Peptides of NY-ESO-1/CAG-3 8/1/2006 E-201-2006/1 7,803,380 8,247,183 Diagnostic and Therapeutic Strategies for Metastatic Hepatocellular Carcinoma by Targeting Osteopontin 8/1/2006 E-086-2006/0 Hybrid T-Cell Receptors for the Development of Improved Vaccines 6/1/2006 E-091-2004/0 Ultrasonic Waves with Nanovessels or Tethered Nanotube/Monoclonal Antibody Composites for Cancer Therapy 6/1/2006 E-090-2004/0 Radio-Activated Boron-Nitride Nanotube-Antibody Conjugates for Cancer Therapy and Diagnostics 6/1/2006 E-325-2003/0 7,790,473 Biofunctionalized Quantum Dots for Biological Imaging 5/1/2006 E-139-2005/0 Identification of a Novel Folliculin Interacting Protein, FNIP-1 3/1/2006 E-258-2005/0 Method for Determining Redox Status of a Tissue 3/1/2006 E-307-2005/0 Use of CYP1B1*3 Genotyping to Predict Survival to Docetaxel Treatment in Androgen-Independent Prostate Cancer 2/1/2006 E-057-2006/0 Autoantibody Screening for Cancer Diagnosis 2/1/2006 E-065-2002/0 ELISA Assay of Serum Soluble CD22 to Assess Tumor Burden/Relapse in Subjects with Leukemia and Lymphoma 12/1/2005 E-323-2003/0 7,589,181 7,915,396 Minimally Immunogenic Variants of SDR-Grafted Humanized Antibody CC49 and Their Use 12/1/2005 E-210-2005/0 Mitotic Spindle ASPM as a Diagnostic Marker for Neoplasia and Uses Thereof 12/1/2005 E-142-1990/2 5,731,167 7,939,635 Autotaxin: Motility Stimulating Protein Useful in Cancer Diagnosis and Therapy 12/1/2005 E-152-2002/0 E-152-2002/1 Quantitative Assay of the Angiogenic and Antiangiogenic Activity of a Test Molecule 11/1/2005 E-217-2005/0 Antibodies Against Insulin-Like Growth Factor II and Uses Thereof 11/1/2005 E-192-2004/0 Compositions and Methods for Diagnosis and Treatment of Chemotherapy-Resistant Neoplastic Disease 10/1/2005 E-266-1994/1 6,428,788 Compositions and Methods of Specifically Targeting Tumors 9/1/2005 E-124-2004/0 E-124-2004/1 E-124-2004/2 7,901,881 Diagnostic Tool for Diagnosing Benign Versus Malignant Thyroid Lesions 7/1/2005 E-208-2005/0 Anti-CD30 Antibodies that Bind to Intact CD30 but not to Soluble CD30 7/1/2005 E-015-2005/0 Anti-Mesothelin Antibodies Useful for Immunological Assays 6/1/2005 E-339-2004/0 7,855,276 Framework Residue Substituted Humanized COL-1 Antibodies and Their Use 5/1/2005 E-041-2005/0 8,409,808 HK1115166 Methods for Detecting Progression of Low Grade Cervical Dysplasia 4/1/2005 E-265-1994/0 E-265-1994/1 Nucleotide and Deduced Amino Acid Sequences of a New Tumor Gene, Int6 4/1/2005 E-324-2001/2 8,283,122 Selections of Genes and Methods of Using the Same for Diagnosis and for Targeting the Therapy of Select Cancers 4/1/2005 E-190-2002/2 7,485,709 8,003,764 Identification of Novel Birt-Hogg-Dubé (BHD) Gene 3/1/2005 E-101-2005/0 Karyotypic Complexity as a Determinant of Anti-Cancer Drug Activity 3/1/2005 E-105-2004/0 E-105-2004/1 Minimally Immunogenic Germline Sequence Variants of COL-1 Antibody and Their Use 3/1/2005 E-108-2004/0 E-234-2003/0 7,711,492 Methods for Identifying, Diagnosing, and Predicting Survival of Lymphomas 2/1/2005 E-324-2001/0 7,774,143 7,783,431 8,062,092 Methods for Analyzing High Dimensional Data for Classifying, Diagnosing, Prognosticating, and/or Predicting Diseases and Other Biological States 2/1/2005 E-324-2001/1 7,655,397 8,263,759 Selections of Genes 1/1/2005 E-269-2003/0 Composition for Detecting the Response of Rectal Adenocarcinomas to Radiochemotherapy 1/1/2005 E-123-2001/0 E-124-2001/1 7,247,615 Peptide Agonists of Prostate-Specific Antigen and Uses Thereof 1/1/2005 E-051-2003/0 Recombinant Immunotoxin and Use in Treating Tumors 10/1/2004 E-059-2004/0 7,947,289 8,388,933 Multimeric Protein Toxins to Target Cells Having Multiple Identifying Characteristics 8/1/2004 E-094-2004/0 Pharmacodynamic Assay 6/1/2004 E-112-1994/0 5,652,223 5,981,712 6,790,936 DNA Encoding CAI Resistance Proteins and Uses Thereof 5/1/2004 E-027-2004/0 Rapid Integration Site Mapping 3/1/2004 E-338-2003/0 Methods for Imaging the Lymphatic System Using Dendrimer-Based Contrast Agents 2/1/2004 E-046-1991/3 6,673,559 Met Proto-Oncogene and a Method for Predicting Breast Cancer Progression 2/1/2004 E-049-2003/0 7,554,090 UltraRad – A Method and Probe to Enhance Radiation Delivery 2/1/2004 E-244-2002/0 Glioma-Selective Polypeptides, Alone or Coupled to a Therapeutic/Diagnostic Agent, Compositions Comprising Same, and Uses Thereof 2/1/2004 E-227-2001/0 7,375,206 Brother of the Regulator of Imprinted Sites (BORIS) 1/1/2004 E-039-2003/0 8,168,568 Combinatorial Therapy for Protein Signaling Diseases 12/1/2003 E-211-1998/0 Methods for Detecting Cancer Cells 11/1/2003 E-083-2003/0 Intracellular Trapping of Radionuclides by Enzyme-Mediated Reduction 11/1/2003 E-253-2002/0 Compositions and Methods for Detecting Abnormal Cell Proliferation 7/1/2003 E-190-2000/0 Methods and Compositions for Inhibiting HIV-Coreceptor Interactions 7/1/2003 E-320-2002/0 E-320-2002/1 7,255,993 Detection of Mutational Frequency in Human Bone Marrow 6/1/2003 E-091-2002/0 7,329,502 7,981,610 Zap70 Protein Expression as a Marker for Chronic Lymphocytic Leukemia (CLL) 4/1/2003 E-233-2002/0 Method of Distinguishing Epithelioid Melanoma from Fibroblastoid Melanoma 3/1/2003 E-003-1991/0 Methods of Screening for Risk of Cancer Using Human Lactoferrin DNA Probe or Primer 3/1/2003 E-057-1994/2 5,844,075 6,270,778 6,537,560 6,965,017 7,232,887 7,612,044 7,745,212 7,749,719 7,763,586 7,803,614 7,807,805 8,030,280 8,273,724 gp100 Cancer Antigens 12/1/2002 E-156-1999/0 Pyrimidine Phosphorylase as a Target for Imaging and Therapy 12/1/2002 E-013-2002/0 7,569,673 7,919,607 Humanized Anti-TAG 72 CC49 for Diagnosis and Therapy of Human Carcinomas 11/1/2002 E-196-2001/0 Use of Interferon-Inducible 2',5'-Oligoadenylate-Dependent RNase in the Diagnosis, Prognosis, and Treatment of Prostate Cancer 9/1/2002 E-300-2001/0 7,432,349 8,026,350 New Tumor Suppressor Gene, p28ING5 5/1/2002 E-225-2001/0 MRP8, A Member of the ABC Transporter Superfamily Highly Expressed in Breast Cancer, and Uses Thereof 1/1/2002 E-161-2000/0 XAGE-1, A Gene Expressed in Multiple Cancers and Uses Thereof 1/1/2002 E-064-2001/0 6,951,761 Parallel Measurements of Multiple Macromolecules Using a Cryoarray 1/1/2002 E-002-2001/0 Tumor Antigen Homologous to Poly(A) Polymerase 11/1/2001 E-261-1998/0 6,969,614 Methods and Devices for Isolation and Analysis of Cellular Protein Content 6/1/2001 E-053-2001/0 PRAC & PRAC-Y: Small Nuclear Proteins Found in Prostate and Colon Cancer, and Uses Thereof 5/1/2001 E-203-1994/0 5,693,779 Production and Use of Anti-Dorsalizing Morphogenetic Protein 3/1/2001 E-336-1987/1 5,693,778 ARG, A Human Gene Related to but Distinct from ABL Proto-Oncogene 2/1/2001 E-237-2000/0 RASS1: A Novel Tumor Suppressor Gene Activated by Ras to Promote Apoptosis 12/1/2000 E-100-2000/0 Usage of Two Yeast Strains in the Identification of Specific Inhibitors of Polo Kinases 12/1/2000 E-014-2000/0 6,600,018 7,223,853 7,947,651 8,158,603 Secreted Frizzled Related Protein, sFRP, Fragments and Methods of Use Thereof 12/1/2000 E-170-2000/0 7,141,661 NAG-1: A Non-Steroidal Anti-Inflammatory Drug Related Gene Which Has Anti-Tumorigenic Properties 12/1/2000 E-259-2000/0 6,759,525 Protein Kinase A and the Carney Complex 5/1/2000 E-173-1998/0 6,995,018 Assay for the Detection of a Variety of Tumors in Biological Specimens 4/1/2000 E-201-1992/0 Monoclonal Antibody Specific to Prostate Cells 4/1/2000 E-194-1998/0 6,441,156 6,979,724 Calcium Channel Compositions and Methods of Use Thereof 9/1/1999 E-112-1999/0 7,008,768 7,563,573 Method For Detecting Radiation Exposure 7/1/1999 E-077-1999/0 6,623,960 7,524,939 Monoclonal Antibodies Specific And Inhibitory To Human Cytochrome P450 2C8, 2C9, 2C18 And 2C19 - New Avenues For Drug Discovery 6/1/1999 E-032-1995/0 5,650,627 Sensitive Assay for Measuring Gallium Levels in Body Tissues and Fluids 5/1/1999 E-137-1990/0 6,221,620 Monoclonal Antibodies Specific for Human Thymidylate Synthase 4/1/1999 E-157-1994/1 6,787,306 7,402,387 Method and Composition for Detecting Dihydropyrimidine Dehydrogenase Splicing Mutations 3/1/1999 E-253-1997/0 PB39, A Novel Isolated Complete cDNA Whose Function is Dysregulated in Prostate Cancer 2/1/1999 E-193-1995/0 Methods for Determining the Prognosis of Breast Cancer Using Antibodies Specific for Thymidylate Synthase 1/1/1999 E-218-1992/0 5,580,760 Novel FUSE-Binding Protein And cDNA 10/1/1997 E-018-1997/0 6,562,589 7,232,890 AIB-1, A Steroid Receptor Co-Activator Amplified In Breast And Ovarian Cancer 8/1/1997 E-094-1997/0 7,358,347 MEN1, The Gene For Multiple Endocrine Neoplasia Type 1 5/1/1997 E-183-1996/0 E-219-1995/0 5,831,016 5,840,839 6,083,703 6,087,110 6,132,980 7,001,600 7,015,312 Novel Human Cancer Antigen of Tyrosinase-Related Proteins 1 and 2 and Genes Encoding Same 5/1/1997 E-046-1997/0 6,060,253 Agents That Bind To And Inhibit Human Cytochrome P450 2D6 11/1/1996 E-088-1996/0 7,709,002 Point Mutated ras Peptides for the Generation of CD8+ Cytotoxic T Lymphocytes 11/1/1996 E-185-1995/0 5,939,530 Inhibitory And Non-Inhibitory Antigen Binding Polypeptides Against Human P450 Enzymes 9/1/1996 E-002-1993/0 Colon Mucosa Gene Having Down-Regulated Expression In Colon Adenomas And Adenocarcinomas 7/1/1996 E-044-1991/2 6,566,098 7,605,127 Truncated Hepatocyte Growth Factor Variants 7/1/1996 E-221-1989/0 E-221-1989/1 5,820,859 5,916,755 Novel Epidermal Growth Factor Receptor (ErbB-3) And Antibodies 4/1/1996 E-184-1993/0 5,518,885 5,654,406 ERBB2 Promoter Binding Protein In Neoplastic Disease 4/1/1996 E-029-1990/0 E-029-1990/1 5,702,907 5,811,262 Hepatocellular Carcinoma Oncogene 4/1/1994 E-116-1992/0 5,569,602 The First Immortalized Kaposi's Sarcoma Cell Line 1/1/1994 E-253-1993/0 5,709,996 5,716,620 5,744,142 5,756,284 5,871,998 5,985,610 Self-Assembling Recombinant Papillomavirus Capsid Proteins Back

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